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The recommended temperature range for the working site is 15-25°C, the sequencers generally produce a lot of heat. For example, the maximum thermal output of the 3130 and 3130xl instruments is 6800 Btu/h (~2000 W). Assuming the instrument is running most of the time it is definitely worth considering the air-conditioning system to be installed. There are, however, additional factors like the size and orientation of the room etc. We recommend you consult us.