The manufacturer’s (Thermo Fisher Scientific, previously Life Technologies, previously Applied Biosystems) policy is to sell new sequencers directly, without resellers. This is why we cannot quote a new sequencer. The problem you will be facing immediately when you start considering a new sequencer is that the new series of sequencers available is somehow limited. The machine with the lowest throughput is the eight-capillary model 3500 (approx. 100-200 samples a day), and that is too many samples for smaller labs. 3500/xl series is also very expensive. Even if you have enough samples to feed the machine, it is still wise to consider purchasing two smaller sequencers (i.e. two four-capillary instruments instead of one eight-capillary) – this gives you broader options how to run samples in parallel with different goals/applications and you are going to have a backup unit if one of these sequencers malfuntions. The price will most likely still be better than for the new 3500!